MCAS
Mast Cell Activation Syndrome (MCAS): A New Epidemic The Common Node of Long COVID, Lyme Disease, Mold Toxicity, and the Modern Chronic Illness Crisis Yoon Hang Kim, MD, MPH | Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Direct Integrative Care | Membership-Based Integrative Telemedicine | May 2026 ⚠ MEDICAL DISCLAIMER This article
MCAS
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician MEDICAL DISCLAIMER This article is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Mast Cell Activation Syndrome (MCAS) and histamine intolerance are highly individualized conditions, and probiotic responses can vary substantially
CIRS
By Yoon Hang Kim, MD, MPH | Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Chronic illness patients — especially those navigating mold illness, Lyme disease, autoimmune conditions, or post-infectious syndromes — frequently encounter two acronyms that are both confusing and critically important: CIRS and MCAS. These conditions share a great deal
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Yoon Hang “John” Kim, MD, MPH Board-certified in Preventive Medicine and Integrative & Holistic Medicine • Direct Integrative Care Ketotifen is a dual-action second-generation H1 antihistamine and partial mast cell stabilizer that has been used for decades in allergology and is increasingly positioned in functional medicine as bridge therapy for mast
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Yoon Hang “John” Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine MD www.directintegrativecare.com Abstract Vitamin D has emerged as a pleiotropic immunomodulatory hormone with significant effects on mast cell biology. Mast cells, which are central effectors in allergic disease and increasingly recognized as drivers of
ldn
Abstract Methylene blue has re-emerged as a promising therapeutic agent in functional and integrative medicine. This article reviews the historical journey of methylene blue from its origins through its pioneering use as t its current applications in mitochondrial support and neuroprotection.
MCAS
An Evidence-Based Guide to LDN, Ketotifen, and Integrative Therapies Yoon Hang Kim, MD, MPH Mast Cell Activation Syndrome (MCAS) is a complex and often underdiagnosed condition in which mast cells—an essential part of the immune system—become dysregulated and release mediators like histamine, prostaglandins, and cytokines inappropriately. This can