Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Medical Disclaimer: This article is for educational and informational purposes only. It does not constitute medical advice, diagnosis, or treatment. Fecal microbiota transplantation is a regulated medical therapy—do not attempt this outside a supervised
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Introduction: A Question Worth Asking Honestly Extracorporeal Blood Oxygenation and Ozonation (EBOO) has gained significant traction in integrative and functional medicine. Blood is drawn from one vein, passed through a hollow-fiber dialysis-style cartridge
A Monograph for the Integrative Clinician Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine Integrative & Functional Medicine Physician Medical Disclaimer: This monograph is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Heat-based interventions carry real risks including burns, scarring, infection, cardiovascular
How Multiple Upstream Triggers Converge on Mast Cell Dysregulation Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Disclaimer: This content is for educational and informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider for
Dosing Nuance, Sensitive Clients, Pain Pathways, and What the Published Literature Does and Does Not Support Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician www.directintegrativecare.com Disclaimer: This blog post is intended for educational and informational purposes only. It does not constitute
WWW.DIRECTINTEGRATIVECARE.COM · MAST CELL ACTIVATION SYNDROME Compounded Amlexanox for MCAS: What the Evidence Actually Supports An old Japanese anti-allergy drug is being repositioned as a mast cell therapy. The mechanism is interesting. The human evidence is not what the marketing suggests — and the dose being prescribed does not
www.directintegrativecare.com ApoB/ApoA1 Ratio vs. NMR LDL Particle Number: Which Lipid Marker Actually Predicts Your Cardiovascular Risk? A comparative clinical review of two advanced lipid markers — and why the choice between them matters more than most standard cholesterol panels reveal. MEDICAL DISCLAIMER This article is for educational purposes
Beyond LDL Cholesterol: Why Your Lipid Testing Strategy Determines Whether Statin Therapy Is Worth the Risk Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician www.directintegrativecare.com One of the most consequential—and underappreciated—decisions in preventive cardiology is not whether to recommend
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician www.directintegrativecare.com If you have had your cholesterol checked and been told the numbers look fine, that is usually good news—and for many people, it is the whole story. But for a specific
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Disclaimer This article is for educational purposes only and does not constitute medical advice. It summarizes published research on sex differences in autoimmune disease and is not intended to diagnose, treat, or guide individual clinical
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Medical Disclaimer: This article is for educational purposes only and does not constitute medical advice. The information presented reflects current preclinical and early clinical research and should not be used as a substitute for professional
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Medical Disclaimer This article is for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any new treatment, including low-dose naltrexone. Nothing in this
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Disclaimer: This article is for educational purposes only and does not constitute medical advice. The information presented reflects a clinical decision-making framework and should not be used as a substitute for individualized care from
genetics LDN
What the Emerging Research Tells Us — and What It Doesn't — About Genetic Influences on Naltrexone Response, Including Low-Dose Naltrexone (LDN) Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Medical Disclaimer: This article is for educational and informational purposes only and
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Few topics in the MCAS world have generated as much excitement — and as much premature confidence — as the idea of using GLP-1 receptor agonists at sub-therapeutic doses to calm mast cell activation. Social
By Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Most people know endorphins as the "feel-good" chemicals behind a runner's high. But endorphins are far more than a post-workout reward signal—they are potent endogenous opioid peptides
10 Evidence-Based Ways to Naturally Increase Your Endorphins By Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Endorphins are among the most powerful natural molecules your body produces — and yet most people have only a vague sense of what they actually are
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Low dose naltrexone (LDN) has become a cornerstone tool in integrative and functional medicine for autoimmune disease, chronic pain, fibromyalgia, mast cell activation syndrome (MCAS), and a growing list of neuroinflammatory conditions. Most clinicians who
LDN Primer Follow-Up: What to Do When LDN Causes Side Effects A companion piece to the LDN Primer book, exploring how side effects are actually managed in clinical practice. LDN Primer Link: One of the questions I hear most often from readers of my LDN Primer book — and from
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician What this article is — and is not. This is a hypothesis. It proposes a biologically plausible, testable model in which low-dose naltrexone (LDN) might indirectly influence purinergic “cell danger” signaling and, in turn, inflammation-
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician ⚕ Medical Disclaimer This article is for educational and informational purposes only and does not constitute medical advice, diagnosis, or treatment. The strategies discussed should be implemented only under the guidance of a qualified healthcare provider.
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Published: July 2026 | www.directintegrativecare.com Medical Disclaimer: This article is intended for educational and clinical reference purposes only. It does not establish a physician–client relationship. All therapeutic decisions must be made by the
endometriosis
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician For many women living with endometriosis, hysterectomy is offered — and often accepted — as the "definitive" solution to years of debilitating pelvic pain. Yet a meaningful number of women are dismayed to discover that
LDN MCAS
Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician July 2026 ⚠ IMPORTANT MEDICAL DISCLAIMER This article is for educational and informational purposes only and does not constitute medical advice, diagnosis, or treatment. Low-dose naltrexone (LDN) is not FDA-approved for mast cell activation