Chronic Pain, Non-Restorative Sleep, and Brain Fog as a Self-Reinforcing Cycle By Yoon Hang “John” Kim, MD, MPH Board-Certified Integrative Medicine Physician | Direct Integrative Care Abstract Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a complex, multi-system illness that remains a diagnosis of exclusion. While its etiology is incompletely understood,
Chronic Fatigue Syndrome (CFS) and Myalgic Encephalomyelitis (ME) remain among the most misunderstood, underdiagnosed, and poorly managed conditions in modern medicine.
Yoon Hang Kim, MD, MPH Board Certified in Preventive Medicine Diplomate of American Board of Medical Acupuncture Diplomate of American Board of Holistic & Integrative Medicine Abstract Depression remains a leading cause of disability worldwide, and a substantial proportion of patients do not achieve adequate remission with first-line pharmacotherapy or
1:11pm I tried LDN several times and stopped because it felt like too much. Then I read about people who are very medication-sensitive — low endorphin, nervous-system dysregulated types — and that sounds like me. It’s developed into chronic pain. I’m very deconditioned. There’s swelling and discoloration. Both
Autoimmune Diets, Ketosis, and Low-Dose Naltrexone:A Layered Strategy for Immune Modulation
7:25pm 321. Recording. So what a great great question. I think this is from Nicholas. The spin off phenol Alan help raising endorphins? So it's a little, I think, not not straightforward because I think that we we think that I think that the phenylalanine, pyroxene, those
LDN represents something powerful.
How Postmenopausal Bone Loss Mobilizes Lead and Other Heavy Metals Into the Bloodstream By Yoon Hang Kim, MD, MPH Board-Certified Preventive Medicine | Integrative & Functional Medicine | LDN Research Trust Presenter When I talk with women navigating perimenopause and menopause, the conversation usually centers on hot flashes, mood changes, sleep disruption,
Keeping Our Community Safe & Thriving A Comprehensive Strategy Guide for Content Compliance, Moderation & Platform Resilience Prepared by Dr. Yoon-Hang Kim February 2026 Executive Summary The LDN Support Group is one of the oldest and most established Low Dose Naltrexone communities on Facebook with over 8,000 members. This
By Yoon Hang Kim, MD, MPH, FAAMA When a patient asked me to look into Low Dose Naltrexone for her autoimmune condition back in 2015, I had no idea that moment would reshape the way I practice medicine. What I found was a medication with a remarkable safety profile, an
A Step-by-Step Guide to Lasting Relief Important Disclaimer This handout is for educational purposes only and does not constitute medical advice. Always consult with your healthcare provider before making any changes to your treatment plan. What Is SIBO? SIBO stands for small intestinal bacterial overgrowth. Normally, relatively few bacteria live
What Is SIBO? SIBO occurs when bacteria that normally live in the large intestine migrate and overgrow in the small intestine. The small intestine is designed to have relatively few bacteria. When excessive bacteria colonize this area, they ferment food prematurely, producing gas and triggering a cascade of digestive and
MCAS
Yoon Hang “John” Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine MD www.directintegrativecare.com Abstract Vitamin D has emerged as a pleiotropic immunomodulatory hormone with significant effects on mast cell biology. Mast cells, which are central effectors in allergic disease and increasingly recognized as drivers of
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Feb 14, 2026 10:30 am FB Live Session What I’ve Learned from Two Decades of Prescribing Low Dose Naltrexone By Yoon Hang Kim, MD, MPH www.directintegrativecare.com I had a conversation with my LDN community recently—a live session where people brought their real questions, their real
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Why the FDA’s Black Box Warning Doesn’t Apply to Low-Dose Naltrexone Yoon Hang Kim, MD, MPH Board Certified in Preventive Medicine | Fellowship Trained Integrative Medicine Physician | Institute of Functional Medicine Scholarship Recipient Direct Integrative Care | www.directintegrativecare.com If you’ve ever Googled naltrexone and liver safety, you’
On root cause medicine: “I didn’t know that I loved integrative medicine because I thought that’s more of a root cause than conventional medicine.”
gut restoration
5R protocol. It’s elegant, logical, and for many patients, it works. Remove the offending agents. Replace what’s missing. Reinoculate with beneficial organisms. Repair the mucosal lining. Rebalance lifestyle factors.
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Article of interest - Determining Optimal Beginning LDN Dose Abstract A common concern among patients considering low-dose naltrexone (LDN) therapy is whether chronic opioid receptor blockade might deplete endogenous endorphins, potentially causing dysphoria, anhedonia, or increased pain sensitivity. This comprehensive review examines the theoretical mechanisms, clinical evidence, and practical implications
magnesium
Yoon Hang Kim, MD, MPH Abstract Magnesium is an essential mineral required for hundreds of enzymatic reactions, yet nearly half of U.S. adults fail to meet recommended dietary allowances. While various magnesium supplements are available, they differ significantly in bioavailability, gastrointestinal tolerance, and evidence for specific clinical indications. This
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Yoon Hang “John” Kim, MD, MPH Board-Certified in Preventive Medicine | www.directintegrativecare.com February 2026 Key Takeaways * Autoimmune disease incidence and prevalence rise markedly with age, particularly after age 60, with some conditions peaking around age 70. * Immune aging (“immunosenescence”) drives this trend through thymic involution, T-cell senescence, impaired regulatory
hexane
Chronic n-Hexane Exposure: An Overlooked Occupational Neurotoxin
yoon hang kim
Yoon Hang Kim, MD, MPH Board-Certified Preventive Medicine | Integrative & Functional Medicine LDN Expert | LDN Research Trust Presenter www.directintegrativecare.com I use works of great minds in my practice and this was brought to my attention from FB Group Root Cause Wellness Hub - https://www.facebook.com/groups/
Analysis & Summary Host: Dr. Yoon-Hang Kim Duration: Approximately 55 minutes (10:28 AM – 11:22 AM CST) Format: Facebook Live Q&A with real-time viewer comments 1. Session Overview Dr. Yoon-Hang Kim hosted his regular Saturday morning live stream Q&A session for the LDN Support Group.
Walhs Protocol
By Dr. Yoon Hang Kim, MD, MPH | Board Certified in Preventive Medicine | Integrative, Functional, and Lifestyle Medicine Physician & LDN Expert Few stories in the world of integrative medicine illustrate the power of a root cause approach more vividly than that of Dr. Terry Wahls. A board-certified internal medicine physician