Integrative Functional Medicine and LDN Community (Page 3)

folate

Folate, Folic Acid, and Folinic Acid - Biochemistry, Clinical Pharmacology, and Integrative Applications

CHAPTER Folate, Folic Acid, and Folinic Acid Biochemistry, Clinical Pharmacology, and Integrative Applications A Comprehensive Review for Clinicians, Researchers, and Students Prepared for Academic Publication Abstract Vitamin B9 exists in three distinct forms that are frequently, and incorrectly, treated as interchangeable. Folate refers to the naturally occurring reduced tetrahydrofolate derivatives

b6

Vitamin B6 (Pyridoxine) Toxicity: Potential Role of LDN

Clinical Recognition, Diagnostic Workup, Evidence-Based Management,and Functional Medicine Considerations Yoon Hang Kim, MD, MPH Board-Certified, Preventive MedicineIntegrative & Functional Medicine Table of Contents Introduction Vitamin B6, a collective term encompassing pyridoxine, pyridoxal, and pyridoxamine and their phosphorylated derivatives, plays an indispensable role in human biochemistry. As the

ME

Diagnosing ME/CFS: Beyond Diagnosis by Exclusion

By Yoon Hang "John" Kim, MD, MPH There is a phrase that has followed myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) for decades: diagnosis of exclusion. Taken too literally, it implies that clinicians arrive at ME/CFS only after exhausting every other possibility — as though the diagnosis is

rapamycine

Rapamycin (found in Rapa Nui or Easter Island) Beyond Transplant Medicine: Longevity, Mast Cell Activation Syndrome, and Autoimmune Disease Through a Functional Medicine Lens

Yoon Hang "John" Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Abstract Rapamycin (sirolimus), an mTOR inhibitor originally developed for transplant immunosuppression, has emerged as the most extensively studied pharmacologic candidate for mammalian lifespan extension and is now being explored for immune dysregulation conditions

breast cancer

A CLINICAL DISCUSSION: Hormone Replacement Therapy After Breast Cancer A Multidisciplinary Case Discussion

BY Yoon Hang Kim, MD, MPH ◆ ◆ ◆ When Standard Guidance Meets Unusual Biology HYPOTHETICAL CASE DISCUSSION For educational and clinical reasoning purposes only EXECUTIVE SUMMARY The Question at the Center of This Case A postmenopausal woman with a complex breast cancer history sits at the intersection of three competing risks: progressive

LDN Support Group FB Q&A Aug 28, 2026 5:05 PM Central Time

LDN Q&A: Neuropathic Pain, MCAS, Insomnia, Microdosing, and What to Do When LDN Causes Side Effects Low dose naltrexone (LDN) is often discussed as though there is one standard dose, one predictable response, and one straightforward way to use it. In clinical practice, it is rarely that simple.

Mast Cell Activation Syndrome Versus Mastocytosis - Distinguishing Activation from Proliferation in Clinical Practice

Yoon Hang Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician Important: This article is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Mast cell disorders require individualized evaluation by qualified specialists. If you experience symptoms suggestive of anaphylaxis — airway compromise,

A CLINICAL DISCUSSION Hormone Replacement Therapy After Breast Cancer A Multidisciplinary Case Discussion

BY Yoon Hang Kim, MD, MPH ◆ ◆ ◆ When the Blanket Contraindication Doesn't Quite Fit HYPOTHETICAL CASE DISCUSSION For educational and clinical reasoning purposes only EXECUTIVE SUMMARY The Question at the Center of This Case A postmenopausal woman with a complex breast cancer history sits at the intersection of three

saffron

Saffron for Sleep: What the Evidence Actually Says — and How It Stacks Up Against Melatonin

By Yoon Hang "John" Kim, MD, MPH Most of my patients who struggle with sleep have already tried melatonin. Some of them are taking 10 mg — or more — every night, and they're still staring at the ceiling. When I bring up saffron, I usually get the

Understanding Fatty Liver Disease - Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

A Guide for Patients and Their Families If your doctor told you that you have a "fatty liver," you're not alone — and it doesn't mean you did anything wrong. This is one of the most common liver conditions in the world, and the good

amlexanox

Amlexanox for MCAS and Long COVID: What Does the Evidence Actually Show?