Yoon Hang Kim MD

Board certified preventive medicine physician. University of Arizona fellowship grad. 20+ years prescribing LDN for chronic pain, autoimmune conditions & complex cases. Author. International speaker. Helping patients find answers.

Vitamin D as a Mast Cell–Modulating Hormone:Mechanistic Evidence, Clinical Implications, and Relevance to Mast Cell Activation Syndrome

MCAS

Vitamin D as a Mast Cell–Modulating Hormone:Mechanistic Evidence, Clinical Implications, and Relevance to Mast Cell Activation Syndrome

Yoon Hang “John” Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine MD www.directintegrativecare.com Abstract Vitamin D has emerged as a pleiotropic immunomodulatory hormone with significant effects on mast cell biology. Mast cells, which are central effectors in allergic disease and increasingly recognized as drivers of

By Yoon Hang Kim MD

ldn

Does Low-Dose Naltrexone Cause Endorphin Deficiency? Separating Mechanism from Myth in LDN Therapy

Article of interest - Determining Optimal Beginning LDN Dose Abstract A common concern among patients considering low-dose naltrexone (LDN) therapy is whether chronic opioid receptor blockade might deplete endogenous endorphins, potentially causing dysphoria, anhedonia, or increased pain sensitivity. This comprehensive review examines the theoretical mechanisms, clinical evidence, and practical implications

By Yoon Hang Kim MD