Board certified preventive medicine physician. University of Arizona fellowship grad. 20+ years prescribing LDN for chronic pain, autoimmune conditions & complex cases. Author. International speaker. Helping patients find answers.
low histamine diet
www.directintegrativecare.com Yoon Hang Kim, MD, MPH | www.directintegrativecare.com MEDICAL DISCLAIMER: This article is intended for educational purposes only and does not constitute medical advice. The information provided should not be used to diagnose, treat, or manage any medical condition. Individual responses to dietary interventions and probiotics vary
Yoon Hang "John" Kim, MD, MPH www.directintegrativecare.com Abstract Low dose naltrexone (LDN) is widely used in integrative medicine for autoimmune disease, chronic pain, fibromyalgia, inflammatory bowel disease, and select malignancies. Its therapeutic effect is generally attributed to a brief, transient blockade of opioid receptors that triggers
Integrative Oncology
Yoon Hang “John” Kim, MD, MPH | www.directintegrativecare.com An Academic Perspective on Integrative Oncology Why This Synthesis Matters Patients facing a serious cancer diagnosis often arrive at a familiar crossroads. The conventional oncology team hands them a treatment plan — chemotherapy, radiation, surgery, increasingly immunotherapy and targeted agents — and the
Yoon Hang Kim MD Membership-Based Integrative & Functional Medicine · www.directintegrativecare.com The Honest Truth About Low-Dose Naltrexone A Clinician’s Framework for Patients, Providers, and the LDN Community Yoon Hang “John” Kim, MD · Direct Integrative Care After two decades caring for patients with chronic, multi-system illness — and after years
1. LDN is a Modulator, Not a Single-Target Drug LDN (low-dose naltrexone) works as a regulatory agent—balancing immune and nervous system function rather than pushing physiology in one direction. It can help both hyperactive and underactive states, which is why it’s used across autoimmune, neuropathic, and inflammatory conditions.
Functional Medicine
CLINICAL BLOG | INTEGRATIVE MEDICINE Parallel Worlds of Healing: Chinese Medicine’s Spleen and Kidney Schools Meet Functional Medicine Yoon Hang “John” Kim, MD, MPH Board-Certified, Preventive Medicine and Integrative/Holistic Medicine • Direct Integrative Care MEDICAL DISCLAIMER This article is provided for educational purposes only and does not constitute medical advice,
Yoon Hang Kim, MD, MPH | www.directintegrativecare.com In integrative medicine, the question is rarely whether emotional wellbeing matters — decades of data now link positive affect to better cardiovascular outcomes, stronger immune function, and longer life. The more practical question is what specifically a patient can do, today, that has
Integrative Oncology
Cholangiocarcinoma (CCA) is an aggressive malignancy arising from the epithelial lining of the biliary tree. The disease is traditionally divided by anatomic origin into three subtypes: intrahepatic (iCCA, arising from small bile ducts within the liver), perihilar (pCCA, at the hepatic duct confluence), and distal (dCCA, within the extrahepatic bile
Yoon Hang (John) Kim, MD, MPH | Board-Certified in Preventive Medicine | Integrative & Functional Medicine Physician | www.directintegrativecare.com Clinical Overview Elevated blood sugar — whether characterized as insulin resistance, prediabetes, or type 2 diabetes — is one of the most common metabolic problems seen in integrative primary care. Patients frequently inquire about
MCAS
Yoon Hang “John” Kim, MD, MPH Board-certified in Preventive Medicine and Integrative & Holistic Medicine • Direct Integrative Care Ketotifen is a dual-action second-generation H1 antihistamine and partial mast cell stabilizer that has been used for decades in allergology and is increasingly positioned in functional medicine as bridge therapy for mast
peptide
Yoon Hang “John” Kim, MD, MPH, FAAMA • Direct Integrative Care • April 2026 Every so often a topic drifts into my inbox from three directions at once. Right now, peptide bioregulators are that topic. Longevity podcasts talk about them. Patients ask about them by brand name. Colleagues in functional medicine swap
Functional Medicine
FUNCTIONAL MEDICINE PERSPECTIVE By Yoon Hang “John” Kim, MD, MPH Board-Certified in Preventive Medicine and Integrative/Holistic Medicine Yoon Hang Kim MD| directintegrativecare.com KEY CLINICAL POINTS • Obesity is reframed as a hormonal disorder driven by chronic hyperinsulinemia, not simply an energy-balance problem. • Three complementary clinical frameworks — Westman (therapeutic carbohydrate