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CHAPTER Folate, Folic Acid, and Folinic Acid Biochemistry, Clinical Pharmacology, and Integrative Applications A Comprehensive Review for Clinicians, Researchers, and Students Prepared for Academic Publication Abstract Vitamin B9 exists in three clinically distinct forms that are frequently, and incorrectly, treated as interchangeable. Folate refers to the naturally occurring reduced tetrahydrofolate
Clinical Recognition, Diagnostic Workup, Evidence-Based Management,and Functional Medicine Considerations Yoon Hang Kim, MD, MPH Board-Certified, Preventive MedicineIntegrative & Functional Medicine Table of Contents Introduction Vitamin B6, a collective term encompassing pyridoxine, pyridoxal, and pyridoxamine and their phosphorylated derivatives, plays an indispensable role in human biochemistry. As the
By Yoon Hang "John" Kim, MD, MPH There is a phrase that has followed myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) for decades: diagnosis of exclusion. Taken too literally, it implies that clinicians arrive at ME/CFS only after exhausting every other possibility — as though the diagnosis is
Yoon Hang "John" Kim, MD, MPH Board-Certified in Preventive Medicine | Integrative & Functional Medicine Abstract Rapamycin (sirolimus), an mTOR inhibitor originally developed for transplant immunosuppression, has emerged as the most extensively studied pharmacologic candidate for mammalian lifespan extension and is now being explored for immune dysregulation conditions